Guys,
The 5140 I-beams are good for 500 hp, plenty strong for a 350-375 hp build. Get those rods plus the 1- piece forged stainless valves in your motor and you can buzz your motor hard with no worries.
I'd say a good quality 400 or 455 will cost about $3500 if you handle the final assembly, or $4500-5000 if you have a shop build it. Figure around $2400 for quality parts (KB forged pistons, 4340 I-beams, Mahle Plasma moly rings, Crower cam w/ new valve springs, PRW aluminum water pump, stainless valves, stainless roller rockers, new Powerforce balancer, etc.), and around $800-1000 for machine work. You could knock $200 off of those prices if you ran the Sealed Power/ TRW-stlye pistons and the 5140's, but considering how much time, money, and effort it takes to build a motor I'm going with the slightly higher priced rods and pistons for my 455 build.
I have a set of 6x-4's and 6x-8's, but most likely I'm running the -8's to keep the compression friendly at 9.2-9.3:1 with 91 octane here in CA. I'm going to port my heads too, but for those new to building pontiacs it's better to have a good shop w/ Pontiac experience do it, or have a Pontiac guy help you do it.
Geno